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Article

Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals.

PloS one - 1 Jan 2013

Euler Zelda, van Gils Marit J, Boeser-Nunnink Brigitte D, Schuitemaker Hanneke, van Manen Daniëlle

Abstract excerpt

Broadly neutralizing antibodies may protect against HIV-1 acquisition. In natural infection, only 10-30% of patients have cross-reactive neutralizing humoral immunity which may relate to viral and or host factors. To explore the role of host genetic markers in the formation of cross-reactive neutralizing activity (CrNA) in HIV-1 infected individuals, we performed a genome-wide association study (GWAS), in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23372753
DOI: 10.1371/journal.pone.0054684
PMCID: PMC3553002

Genes

MICA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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