Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 envelope glycoprotein signatures that correlate with the development of cross-reactive neutralizing activity

23 Sept 2013

Abstract excerpt

BACKGROUND: Current HIV-1 envelope glycoprotein (Env) vaccines are unable to induce cross-reactive neutralizing antibodies. However, such antibodies are elicited in 10-30% of HIV-1 infected individuals, but it is unknown why these antibodies are induced in some individuals and not in others. We hypothesized that the Envs of early HIV-1 variants in individuals who develop cross-reactive neutralizing activity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Research and Disease Studies
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24059682
DOI: 10.1186/1742-4690-10-102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 envelope glycoprotein signatures that correlate with the development of cross-reactive neutralizing activityPMID 24059682Read ↗

Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 InfectionSemantic proximity Read ↗

Increased immunogen valency improves the maturation of vaccine-elicited HIV-1 VRC01-class antibodiesSemantic proximity Read ↗

Evolutionary Dynamics of the Glycan Shield of theHuman Immunodeficiency Virus Envelope during Natural Infection andImplications for Exposure of the 2G12EpitopeSemantic proximity Read ↗

Limited Evidence for a Relationship between HIV-1 Glycan Shield Features in Early Infection and the Development of Neutralization BreadthSemantic proximity Read ↗

HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bondsSemantic proximity Read ↗

Cross-neutralization of SARS-CoV-2 by HIV-1 specific broadly neutralizing antibodies and polyclonal plasmaSemantic proximity Read ↗

Glycan-Dependent Neutralizing Antibodies Are Frequently Elicited in Individuals Chronically Infected with HIV-1 Clade B or C.Semantic proximity Read ↗

Neutralizing Antibody Responses in Acute Human Immunodeficiency Virus Type 1 Subtype C InfectionSemantic proximity Read ↗

Maturation Pathways of Cross-Reactive HIV-1 Neutralizing AntibodiesSemantic proximity Read ↗

Consistent Induction of Broadly Neutralizing HIV Antibodies by a Novel Two-Step Mechanism Informs Immunogen DesignSemantic proximity Read ↗

Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and ImmunotypesSemantic proximity Read ↗

Broadly Neutralizing Antibodies against HIV-1 As a Novel Aspect of the Immune ResponseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.