Article
Survival is associated with genetic variation in inflammatory pathway genes among patients with resected and unresected pancreatic cancer.
Annals of surgery - 1 Jun 2013
Reid-Lombardo Kaye M, Fridley Brooke L, Bamlet William R, Cunningham Julie M, Sarr Michael G, Petersen Gloria M
Abstract excerpt
OBJECTIVE: To test whether or not the association between inflammation and pancreatic ductal adenocarcinoma (PC) is facilitated by host susceptibility, specifically by genetic polymorphisms in inflammation-related genes. SUMMARY BACKGROUND DATA: Inflammation has been linked to PC. Reports have cited an increased expression of proinflammatory mediators, such as NF-κB and COX, in PC but not in normal adjacent...
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