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Article

Inflammation and RNA-Related Polymorphisms in Resected Cholangiocarcinoma: Prognostic Associations in Intrahepatic and Perihilar Tumors.

Journal of gastrointestinal cancer - 8 Jul 2026

Wang Guanwu, Liu Dong, Al-Masri Tarick M, Lueong Smiths S, Siveke Jens T, Luedde Tom, Vondran Florian W R, Lurje Georg, Neumann Ulf P, Heij Lara R, Bednarsch Jan

Abstract excerpt

BACKGROUND: Cholangiocarcinoma (CCA) is a heterogeneous and aggressive malignancy of the biliary tract, often classified into intrahepatic (iCCA) and perihilar (pCCA) subtypes. Inflammatory and RNA-regulatory pathways are implicated in CCA pathogenesis. However, the prognostic significance of related single nucleotide polymorphisms (SNPs) remains unclear. METHOD: We retrospectively analyzed nine candidate SNPs in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42418091
DOI: 10.1007/s12029-026-01520-z
PMCID: PMC13346121

Genes

TNIP1
CD274
CDKN2B
IL17A
IL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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