Article
Inflammation-related gene variants as risk factors for pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2011
Reid-Lombardo Kaye M, Fridley Brooke L, Bamlet William R, Cunningham Julie M, Sarr Michael G, Petersen Gloria M
Abstract excerpt
BACKGROUND: Recent reports support an association between chronic inflammation and progression to pancreatic cancer (PC). METHODS: This case-control, candidate gene association study evaluated 1,354 Caucasian patients with pancreatic ductal adenocarcinoma and 1,189 healthy Caucasian controls. We genotyped 1,538 single nucleotide polymorphism (SNP) in 102 genes from inflammatory pathways involving NF-κB. Primary...
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