Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms in inflammation pathway genes and prostate cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2011

Kwon Erika M, Salinas Claudia A, Kolb Suzanne, Fu Rong, Feng Ziding, Stanford Janet L, Ostrander Elaine A

Abstract excerpt

BACKGROUND: Chronic inflammation is an important mechanism for the development and progression of prostate cancer (PC). To better understand the potential relationship between genes in the inflammation pathway and PC risk, we evaluated variants in 16 candidate genes. METHODS: A total of 143 tagging and amino acid altering single nucleotide polymorphisms (SNPs) were genotyped in Caucasian and African American men...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Inflammation

Share to Prognosis

Share to Prostatic Neoplasms

Share to Risk Factors

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 21430300
DOI: 10.1158/1055-9965.EPI-10-0994
PMCID: PMC3140053

Genes

STAT3
PTGS2
AKT1
CXCL12
IMPACT
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms in inflammation pathway genes and prostate cancer risk.PMID 21430300Read ↗

PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3).Semantic proximity Read ↗

A comprehensive association study for genes in inflammation pathway provides support for their roles in prostate cancer risk in the CAPS study.Semantic proximity Read ↗

Prostate cancer: from the pathophysiologic implications of some genetic risk factors to translation in personalized cancer treatments.Semantic proximity Read ↗

Interactions of cytokine gene polymorphisms in prostate cancer risk.Semantic proximity Read ↗

Interleukin-6 promoter variants, prostate cancer risk, and survival.Semantic proximity Read ↗

A Multigene-Panel Study Identifies Single Nucleotide Polymorphisms Associated with Prostate Cancer Risk.Semantic proximity Read ↗

Polymorphisms of pro-inflammatory genes and prostate cancer risk: a pharmacogenomic approach.Semantic proximity Read ↗

Interleukins-6 -174G/C (rs1800795) and -572C/G (rs1800796) polymorphisms and prostate cancer risk.Semantic proximity Read ↗

Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer.Semantic proximity Read ↗

Cytokine genetic polymorphisms and prostate cancer aggressiveness.Semantic proximity Read ↗

Association between variants in genes involved in the immune response and prostate cancer risk in men randomized to the finasteride arm in the Prostate Cancer Prevention Trial.Semantic proximity Read ↗

Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.