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Genetic polymorphisms in inflammatory genes and pancreatic cancer risk: a two-phase study on more than 14 000 individuals.

Mutagenesis - 19 Dec 2019

Gentiluomo Manuel, Peduzzi Giulia, Lu Ye, Campa Daniele, Canzian Federico

Abstract excerpt

There is overwhelming evidence that inflammation plays a key role in the pathogenesis of cancer and its progression. Inflammation is regulated through a complex network of genes and polymorphic variants in these genes have been found to be associated to risk of various human cancers, alone or in combination with environmental variables. Despite this, not much is known on the genetic variability of genes that...

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PMID: 31748817
DOI: 10.1093/mutage/gez040

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