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Article

Inferring the kinetics of stochastic gene expression from single-cell RNA-sequencing data.

Genome biology - 28 Jan 2013

Kim Jong Kyoung, Marioni John C

Abstract excerpt

BACKGROUND: Genetically identical populations of cells grown in the same environmental condition show substantial variability in gene expression profiles. Although single-cell RNA-seq provides an opportunity to explore this phenomenon, statistical methods need to be developed to interpret the variability of gene expression counts. RESULTS: We develop a statistical framework for studying the kinetics of stochastic...

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Identifiers

PMID: 23360624
DOI: 10.1186/gb-2013-14-1-r7
PMCID: PMC3663116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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