Article

noSpliceVelo infers gene expression dynamics without separating unspliced and spliced transcripts

2024-08-09

Abstract excerpt

Modern single-cell transcriptomics has revolutionized biological research, but because of its destructive nature, it provides only static snapshots. Computational approaches that infer RNA velocity from the ratio of unspliced to spliced mRNA levels can be used to predict how gene expression changes over time. However, information about unspliced and spliced transcripts is not always available and may change on a t...

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Literature Corpus work: 8ea9236e-eca2-55fa-a0e7-f74b291cc55b
DOI: 10.1101/2024.08.08.607261

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