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Article

Lower cognitive performance in healthy G2019S LRRK2 mutation carriers.

Neurology - 4 Sept 2012

Thaler Avner, Mirelman Anat, Gurevich Tanya, Simon Ely, Orr-Urtreger Avi, Marder Karen, Bressman Susan, Giladi Nir

Abstract excerpt

OBJECTIVE: To assess cognitive abilities of healthy first-degree relatives of Ashkenazi patients with Parkinson disease (PD), carriers of the G2019S mutation in the LRRK2 gene. METHODS: In this observational study, 60 consecutive healthy first-degree relatives (aged 50.9 ± 6.2 years; 48% male; 30 G2019S carriers) were assessed using a computerized cognitive program, the Montreal Cognitive Assessment...

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Identifiers

PMID: 22914834
DOI: 10.1212/WNL.0b013e3182684646
PMCID: PMC3430708

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