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Article

No evidence for BRAF-V600E mutations in gastroeosophageal tumors: results from a high-throughput analysis of 534 cases using a mutation-specific antibody.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Oct 2013

Preusser Matthias, Berghoff Anna S, Capper David, von Deimling Andreas, Maroske Florian, Brodowicz Thomas, Hejna Michael, Birner Peter, Schoppmann Sebastian F

Abstract excerpt

BACKGROUND: BRAF-V600E mutations are found in a broad spectrum of cancer types and can be successfully targeted by specific therapeutic compounds. Little data on the prevalence of BRAF-V600E mutations in tumors of the upper gastrointestinal tract are available. MATERIALS AND METHODS: We constructed tissue microarrays of formalin-fixed and paraffin-embedded specimens of 534 gastroesophageal tumors (119 squamous...

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Source

Identifiers

PMID: 23343956
DOI: 10.1097/PAI.0b013e31827ce693

Genes

BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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