Performance comparison of three BRAF V600E detection methods in malignant melanoma and colorectal cancer specimens.

doi:10.1007/s13277-014-2711-5

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Article

Performance comparison of three BRAF V600E detection methods in malignant melanoma and colorectal cancer specimens.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2015

Løes Inger Marie, Immervoll Heike, Angelsen Jon-Helge, Horn Arild, Geisler Jürgen, Busch Christian, Lønning Per Eystein, Knappskog Stian

Abstract excerpt

Personalized cancer care requires reliable biomarkers. While the BRAF V600E mutation is implemented in the clinic, no method for its detection has so far been established as reference. We aimed to perform a comprehensive comparison of three methods currently being used for V600E detection in clin...

Topics

Biomarkers, Tumor
Colorectal Neoplasms
DNA Mutational Analysis
High-Throughput Nucleotide Sequencing
Humans
Immunohistochemistry
Melanoma
Mutation
Precision Medicine
Proto-Oncogene Proteins B-raf

Source

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Identifiers

PMID: 25318602
DOI: 10.1007/s13277-014-2711-5
PMCID: PMC4342512

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-25318602-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

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Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.