Comparison of similarity-based tests and pooling strategies for rare variants.

Abstract excerpt

BACKGROUND: As several rare genomic variants have been shown to affect common phenotypes, rare variants association analysis has received considerable attention. Several efficient association tests using genotype and phenotype similarity measures have been proposed in the literature. The major advantages of similarity-based tests are their ability to accommodate multiple types of DNA variations within one...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Variation
• Share to Genetics, Population
• Share to Genome-Wide Association Study