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Article

Genetic instability and intratumoral heterogeneity in neuroblastoma with MYCN amplification plus 11q deletion.

PloS one - 1 Jan 2013

Villamón Eva, Berbegall Ana P, Piqueras Marta, Tadeo Irene, Castel Victoria, Djos Anna, Martinsson Tommy, Navarro Samuel, Noguera Rosa

Abstract excerpt

BACKGROUND/AIM: Genetic analysis in neuroblastoma has identified the profound influence of MYCN amplification and 11q deletion in patients' prognosis. These two features of high-risk neuroblastoma usually occur as mutually exclusive genetic markers, although in rare cases both are present in the same tumor. The purpose of this study was to characterize the genetic profile of these uncommon neuroblastomas...

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Source

Open in PubMed Open full text

Identifiers

PMID: 23341988
DOI: 10.1371/journal.pone.0053740
PMCID: PMC3544899

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic instability and intratumoral heterogeneity in neuroblastoma with MYCN amplification plus 11q deletion.PMID 23341988Read ↗

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