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Article

Investigation of major genetic alterations in neuroblastoma.

Molecular biology reports - 1 Jun 2018

Costa Régis Afonso, Seuánez Héctor N

Abstract excerpt

Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. This malignancy shows a wide spectrum of clinical outcome and its prognosis is conditioned by manifold biological and genetic factors. We investigated the tumor genetic profile and clinical data of 29 patients with NB by multiplex ligation-dependent probe amplification (MLPA) to assess therapeutic risk. In 18 of these tumors, MYCN status...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29455316
DOI: 10.1007/s11033-018-4161-4

Genes

MYCN
DCDC2
PKHD1

Provenance

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