Article
Association between HLA-B*46 allele and Graves disease in Asian populations: a meta-analysis.
International journal of medical sciences - 1 Jan 2013
Li Yiping, Yao Yufeng, Yang Man, Shi Li, Li Xianli, Yang Ying, Zhang Ying, Xiao Chunjie
Abstract excerpt
Graves' disease (GD) is a leading cause of hyperthyroidism, which affects 1.0-1.6% of the general population. Previous studies reported a higher GD prevalence in Asian populations compared to Caucasian populations. The etiology of GD involves complex interactions between predisposing genes and environmental triggers. Genetic studies have shown that the human leukocyte antigen (HLA) is an important candidate...
Topics
- Alleles
- Asian People
- Genetic Association Studies
- Graves Disease
- HLA-B Antigens
- Humans
- Risk Factors