Article
mik1(+) G1-S transcription regulates mitotic entry in fission yeast.
FEBS letters - 17 Aug 2001
Ng S S, Anderson M, White S, McInerny C J
Abstract excerpt
In the fission yeast Schizosaccharomyces pombe Mik1p, in combination with Wee1p, is an important inhibitor of mitosis through direct phosphorylation of Cdc2p. Here we present the observation that mik1(+) is transcribed during G1- and S-phase in normally dividing cells. mik1(+) transcription is regulated by the MCB-DSC1 system, which controls expression of other genes at the G1-S interval. mik1(+) is shown to be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.