Article
Impact of natriuretic peptide polymorphisms on diastolic and metabolic function in a populational cohort: insights from the STANISLAS cohort.
ESC heart failure - 1 Feb 2022
Xhaard Constance, Rouget Raphaël, Vodovar Nicolas, Le Floch Edith, Dandine-Roulland Claire, Wagner Sandra, Bacq-Daian Delphine, Thuillier Quentin, Boivin Jean-Marc, Branlant Christiane, Deleuze Jean-François, Behm-Ansmant Isabelle, Zannad Faiez, Rossignol Patrick, Girerd Nicolas
Abstract excerpt
AIMS: Elevated brain natriuretic peptide (BNP) and the N-terminal fragment of its pro-hormone (NT-proBNP) have become established biomarkers for heart failure and are associated with cardiovascular morbidity and mortality. Investigating sources of inter-individual heterogeneity, particularly genetic factors, could help better identify patients at risk of future cardiovascular disease. The aim of this study was to...
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