Article
Association of common variants in NPPA and NPPB with blood pressure does not translate into kidney damage in a general population study.
Journal of hypertension - 1 Jun 2010
Maimaitiming Suliya, Roussel Ronan, Hadjadj Samy, Fumeron Frédéric, Aubert Roberte, Emery Nathalie, Velho Gilberto, Mohammedi Kamel, Travert Florence, Tichet Jean, Alhenc-Gelas Francois, Balkau Beverley, Marre Michel
Abstract excerpt
BACKGROUND: The polymorphisms rs198358, rs5068 and rs632793 in the natriuretic peptide precursor A-B gene region [encoding atrial natriuretic peptides (ANP) and brain natriuretic peptides (BNP)] have been recently associated with ANP and BNP plasma concentrations and blood pressure (BP) in a large cohort study. METHODS: We observed that GCG, the haplotype based on these polymorphisms and combining the three rare...
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