Article
Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states.
Open biology - 1 Oct 2014
Salina Elena G, Waddell Simon J, Hoffmann Nadine, Rosenkrands Ida, Butcher Philip D, Kaprelyants Arseny S
Abstract excerpt
Dormancy in non-sporulating bacteria is an interesting and underexplored phenomenon with significant medical implications. In particular, latent tuberculosis may result from the maintenance of Mycobacterium tuberculosis bacilli in non-replicating states in infected individuals. Uniquely, growth of M. tuberculosis in aerobic conditions in potassium-deficient media resulted in the generation of bacilli that were...
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