Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissecting host factors that regulate the early stages of tuberculosis infection.

Tuberculosis (Edinburgh, Scotland) - 1 Sept 2016

Agrawal Neha, Bhattacharyya Chandrika, Mukherjee Ankur, Ullah Ubaid, Pandit Bhaswati, Rao Kanury V S, Majumder Partha P

Abstract excerpt

Incomplete understanding of mechanisms involved in the host-pathogen interactions constrains our efforts to eliminate tuberculosis. In many individuals, resulting from immune response to mycobacterial infection organised structures called granulomas are formed. To identify host responses that may control at least the early stages of infection, we employed an in vitro granuloma model. Here, human PBMCs were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Colony Count, Microbial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytokines

Share to Granuloma

Share to Host-Pathogen Interactions

Share to Metabolic Networks and Pathways

Share to Mycobacterium tuberculosis

Share to Tuberculosis

Source

Identifiers

PMID: 27553417
DOI: 10.1016/j.tube.2016.07.009

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissecting host factors that regulate the early stages of tuberculosis infection.PMID 27553417Read ↗

Host and bacterial lipid metabolism during tuberculosis infections: possibilities to synergise host- and bacteria-directed therapiesSemantic proximity Read ↗

Recent advances in deciphering the contribution of Mycobacterium tuberculosis lipids to pathogenesisSemantic proximity Read ↗

Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responsesSemantic proximity Read ↗

The Secret Lives of the Pathogenic MycobacteriaSemantic proximity Read ↗

Soluble immune mediators orchestrate protective <i>in vitro</i> granulomatous responses across <i>Mycobacterium tuberculosis</i> complex lineagesSemantic proximity Read ↗

[Tuberculosis: pathogenesis, immune responses and genetics of the host].Semantic proximity Read ↗

Mycobacterium tuberculosis-driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype.Semantic proximity Read ↗

Host-directed therapies targeting the tuberculosis granuloma stromaSemantic proximity Read ↗

GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During Mycobacterium tuberculosis Infection and Is Associated With TB Disease SeveritySemantic proximity Read ↗

Understanding the development of tuberculous granulomas: insights into host protection and pathogenesis, a review in humans and animalsSemantic proximity Read ↗

PPAR<i>γ</i>Expression and Function in Mycobacterial Infection: Roles in Lipid Metabolism, Immunity, and Bacterial KillingSemantic proximity Read ↗

Human granuloma in vitro model, for TB dormancy and resuscitation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.