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Article

The perilipin-like PPE15 protein in Mycobacterium tuberculosis is required for triacylglycerol accumulation under dormancy-inducing conditions.

Molecular microbiology - 1 Sept 2016

Daniel Jaiyanth, Kapoor Nidhi, Sirakova Tatiana, Sinha Rajesh, Kolattukudy Pappachan

Abstract excerpt

Mycobacterium tuberculosis (Mtb) causes latent tuberculosis infection in one-third of the world population and remains quiescent in the human body for decades. The dormant pathogen accumulates lipid droplets containing triacylglycerol (TAG). In mammals, perilipin regulates lipid droplet homeostasis but no such protein has been identified in Mtb. We identified an Mtb protein (PPE15) that showed weak amino acid...

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Identifiers

PMID: 27325376
DOI: 10.1111/mmi.13422
PMCID: PMC5019126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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