Article
Antimicrobial activity against Mycobacterium tuberculosis under in vitro lipid-rich dormancy conditions.
Journal of medical microbiology - 1 Mar 2018
Aguilar-Ayala Diana Angelica, Cnockaert Margo, Vandamme Peter, Palomino Juan Carlos, Martin Anandi, Gonzalez-Y-Merchand Jorge
Abstract excerpt
Although tuberculosis treatment is dependent on drug-susceptibility testing (DST) and molecular drug-resistance detection, treatment failure and relapse remain a challenge. This could be partially due to the emergence of antibiotic-tolerant dormant mycobacteria, where host lipids have been shown to play an important role. This study evaluated the susceptibility of Mycobacterium tuberculosis to two antibiotic...
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