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Article

ANKK1, TTC12, and NCAM1 polymorphisms and heroin dependence: importance of considering drug exposure.

JAMA psychiatry - 1 Mar 2013

Nelson Elliot C, Lynskey Michael T, Heath Andrew C, Wray Naomi, Agrawal Arpana, Shand Fiona L, Henders Anjali K, Wallace Leanne, Todorov Alexandre A, Schrage Andrew J, Saccone Nancy L, Madden Pamela A F, Degenhardt Louisa, Martin Nicholas G, Montgomery Grant W

Abstract excerpt

CONTEXT: The genetic contribution to liability for opioid dependence is well established; identification of the responsible genes has proved challenging. OBJECTIVE: To examine association of 1430 candidate gene single-nucleotide polymorphisms (SNPs) with heroin dependence, reporting here only the 71 SNPs in the chromosome 11 gene cluster (NCAM1, TTC12, ANKK1, DRD2) that include the strongest observed...

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Identifiers

PMID: 23303482
DOI: 10.1001/jamapsychiatry.2013.282
PMCID: PMC3789525

Genes

NCAM1
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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