Article
A single nucleotide polymorphism in OPRM1(rs483481) and risk for heroin use disorder.
Journal of addictive diseases - 1 Jan 2000
Koijam Arunkumar Singh, Chakraborty Barnali, Mukhopadhyay Kanchan, Rajamma Usha, Haobam Reena
Abstract excerpt
Opioid receptor mu1 (OPRM1) is the target of many opioid drugs, and it is known to have affinity toward both endogenous and exogenous opioids, opiate and opioid analgesic drugs. The present study was undertaken to explore association of single nucleotide polymorphisms (SNPs) in the OPRM1 gene with heroin use disorder. Ten OPRM1 polymorphisms were analyzed in 132 cases and 147 healthy controls. The SNP rs483481...
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