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Article

Genetic susceptibility to heroin addiction: a candidate gene association study.

Genes, brain, and behavior - 1 Oct 2008

Levran O, Londono D, O'Hara K, Nielsen D A, Peles E, Rotrosen J, Casadonte P, Linzy S, Randesi M, Ott J, Adelson M, Kreek M J

Abstract excerpt

Heroin addiction is a chronic complex disease with a substantial genetic contribution. This study was designed to identify genetic variants that are associated with susceptibility to develop heroin addiction by analyzing 1350 variants in 130 candidate genes. All subjects had Caucasian ancestry. The sample consisted of 412 former severe heroin addicts in methadone treatment, and 184 healthy controls with no...

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Source

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Identifiers

PMID: 18518925
DOI: 10.1111/j.1601-183X.2008.00410.x
PMCID: PMC2885890

Genes

OPRM1
OPRD1
GAL
OPRK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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