Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dopaminergic pathway polymorphisms and heroin addiction: further support for association of CSNK1E variants.

Pharmacogenomics - 1 Dec 2014

Levran Orna, Peles Einat, Randesi Matthew, Correa da Rosa Joel, Ott Jurg, Rotrosen John, Adelson Miriam, Kreek Mary Jeanne

Abstract excerpt

BACKGROUND & AIM: The dopaminergic pathways have been implicated in the etiology of drug addictions. The aim of this study was to determine if variants in dopaminergic genes are associated with heroin addiction. MATERIALS & METHODS: The study includes 828 former heroin addicts and 232 healthy controls, of predominantly European ancestry. Ninety seven SNPs (13 genes) were analyzed. RESULTS: Nine nominally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analgesics, Opioid
Share to Circadian Rhythm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopamine

Share to Dopamine and cAMP-Regulated Phosphoprotein 32

Share to Genetic Association Studies

Share to Heroin Dependence

Share to Linkage Disequilibrium

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 25521358
DOI: 10.2217/pgs.14.145
PMCID: PMC4288976

Genes

DRD2
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dopaminergic pathway polymorphisms and heroin addiction: further support for association of CSNK1E variants.PMID 25521358Read ↗

Genetic susceptibility to heroin addiction: a candidate gene association study.Semantic proximity Read ↗

Overlapping dopaminergic pathway genetic susceptibility to heroin and cocaine addictions in African Americans.Semantic proximity Read ↗

A 35.8 kilobases haplotype spanning ANKK1 and DRD2 is associated with heroin dependence in Han Chinese males.Semantic proximity Read ↗

Association between heroin dependence and prodynorphin gene polymorphisms.Semantic proximity Read ↗

Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction.Semantic proximity Read ↗

Genetic signatures of heroin addiction.Semantic proximity Read ↗

A population-based association study of casein kinase 1 epsilon loci with heroin dependence in Han Chinese.Semantic proximity Read ↗

Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence.Semantic proximity Read ↗

ANKK1, TTC12, and NCAM1 polymorphisms and heroin dependence: importance of considering drug exposure.Semantic proximity Read ↗

Dopaminergic and Opioid Pathways Associated with Impulse Control Disorders in Parkinson’s DiseaseSemantic proximity Read ↗

Genetic and Epigenetic Approaches to Opioid Use Disorder.Semantic proximity Read ↗

Association of OPRD1 polymorphisms with heroin dependence in a large case-control series.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.