Brain-derived neurotrophic factor serum levels and genotype: association with depression during interferon-α treatment.

doi:10.1038/npp.2012.263

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Article

Brain-derived neurotrophic factor serum levels and genotype: association with depression during interferon-α treatment.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 May 2013

Lotrich Francis E, Albusaysi Salwa, Ferrell Robert E

Abstract excerpt

Depression has been associated with inflammation, and inflammation may both influence and interact with growth factors such as brain-derived neurotrophic factor (BDNF). Both the functional Val66Met BDNF polymorphism (rs6265) and BDNF levels have been associated with depression. It is thus plausible that decreased BDNF could mediate and/or moderate cytokine-induced depression. We therefore prospectively employed...

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PMID: 23303061
DOI: 10.1038/npp.2012.263
PMCID: PMC3629388

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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