Val66Met polymorphism association with serum BDNF and inflammatory biomarkers in major depression.

doi:10.1080/15622975.2017.1347713

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Article

Val66Met polymorphism association with serum BDNF and inflammatory biomarkers in major depression.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Aug 2018

Caldieraro Marco Antonio, McKee Madison, Leistner-Segal Sandra, Vares Edgar Arrua, Kubaski Francyne, Spanemberg Lucas, Brusius-Facchin Ana Carolina, Fleck Marcelo P, Mischoulon David

Abstract excerpt

OBJECTIVES: Current evidence supports participation of neurotrophic and inflammatory factors in the pathogenesis of major depressive disorder (MDD). Some studies reported an association between the Val66Met polymorphism (rs6265) of brain-derived neurotrophic factor (BDNF) gene with MDD and peripheral BDNF levels. However, no previous studies have examined the association of this polymorphism with inflammation....

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PMID: 28656803
DOI: 10.1080/15622975.2017.1347713

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BDNF
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