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Article

Gender-specific association of the interleukin 18 gene with symptomatic gallstone disease.

Journal of gastroenterology and hepatology - 1 Apr 2013

Shih Shou-Chuan, Yang Horng-Woei, Chang Tzu-Yang, Wang Horng-Yuan, Hu Kuang-Chun, Chang Ching-Wei, Chang Chen-Wang, Hung Chien-Yuan, Lin Marie, Chan Hui-Wen, Lin Wen-Shan, Chang Shih-Chuan, Lee Yann-Jinn

Abstract excerpt

BACKGROUND AND AIM: Symptomatic gallstone disease (SGSD) induced several inflammatory responses and affected extrahepatic bile ducts. Although the pathology and environmental risk factors of gallstone disease are well documented, immune or inflammatory responses in SGSD development are still inconclusive. Interleukin 18 (IL18) is a pro-inflammatory cytokine that plays an important role in immune, infectious, and...

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PMID: 23302036
DOI: 10.1111/jgh.12117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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