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Article

Investigation of cytotoxic T-lymphocyte-associated protein 4 gene polymorphisms in symptomatic gallstone disease.

Human immunology - 1 Apr 2011

Shih Shou-Chuan, Yang Horng-Woei, Chang Tzu-Yang, Hu Kuang-Chun, Chang Shih-Chuan, Lin Chiung-Ling, Hung Chien-Yuan, Wang Horng-Yuan, Lin Marie, Lee Yann-Jinn

Abstract excerpt

Gallstone disease (GSD), which is increasingly prevalent in Taiwan, develops through a complex process involving genetic, environmental, and immune factors. Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) limits T-cell proliferation. The present study looked for associations between symptomatic GSD and polymorphisms of the CTLA4 gene. For this case-control cross-sectional study among Taiwanese, 275 patients...

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Identifiers

PMID: 21277929
DOI: 10.1016/j.humimm.2011.01.004

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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