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Article

Interplay between NOD1 polymorphisms and gene expression in the pathogenesis of gallstone disease.

Molecular biology reports - 20 Jan 2026

Murali Sanjana, Vijayaraghavan Shanthi, Shanmugam Rajesh Kumar, Krishnamurthy Nandini, Krishna R B Devi, Ram Pradeep Narahari, Balu Jashwanth, Francis Andrea Mary

Abstract excerpt

BACKGROUND: Gallstone disease (GSD) is a multifactorial disorder with both genetic and inflammatory influences. Nucleotide-binding oligomerization domain containing protein 1 (NOD1) has an important role in innate immunity and in regulation of gut microbiota and its genetic relationship to GSD is unknown. AIM: To explore the association of NOD1 gene polymorphism (rs5743336 and rs6958571) and gene expression with...

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PMID: 41557225
DOI: 10.1007/s11033-026-11465-y

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NOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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