Article
Sterol transporter adenosine triphosphate-binding cassette transporter G8, gallstones, and biliary cancer in 62,000 individuals from the general population.
Hepatology (Baltimore, Md.) - 1 Feb 2011
Stender Stefan, Frikke-Schmidt Ruth, Nordestgaard Børge G, Tybjaerg-Hansen Anne
Abstract excerpt
UNLABELLED: Gallstone disease, a risk factor for biliary cancer, has a strong heritable component, but the underlying genes are largely unknown. To test the hypothesis that ABCG8 (adenosine triphosphate-binding cassette transporter G8) Asp19His (D19H) genotype predicted risk of gallstones and biliary cancer in the general population, we studied 62,279 white individuals from The Copenhagen City Heart Study and The...
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