Article
Inflammatory gene variants and the risk of biliary tract cancers and stones: a population-based study in China.
BMC cancer - 11 Oct 2012
Castro Felipe A, Koshiol Jill, Hsing Ann W, Gao Yu-Tang, Rashid Asif, Chu Lisa W, Shen Ming-Chang, Wang Bing-Shen, Han Tian-Qua, Zhang Bai-He, Niwa Shelley, Yu Kai, Zhang Hong, Chanock Stephen, Andreotti Gabriella
Abstract excerpt
BACKGROUND: Genetic variants in inflammation-related genes have been associated with biliary stones and biliary tract cancers in previous studies. METHODS: To follow-up on these findings, we examined 35 single nucleotide polymorphism (SNPs) in 5 genes related to inflammation (IL8, NFKBIL, RNASEL, TNF, and VEGFA) in 456 participants with incident biliary tract cancer cases (262 gallbladder, 141 extrahepatic bile...
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