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Article

Ichthyosis vulgaris: the filaggrin mutation disease.

The British journal of dermatology - 1 Jun 2013

Thyssen J P, Godoy-Gijon E, Elias P M

Abstract excerpt

Ichthyosis vulgaris is caused by loss-of-function mutations in the filaggrin gene (FLG) and is characterized clinically by xerosis, scaling, keratosis pilaris, palmar and plantar hyperlinearity, and a strong association with atopic disorders. According to the published studies presented in this review article, FLG mutations are observed in approximately 7·7% of Europeans and 3·0% of Asians, but appear to be...

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Source

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Identifiers

PMID: 23301728
DOI: 10.1111/bjd.12219
PMCID: PMC6317863

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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