Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Filaggrin gene mutations are frequent and increase the risk of skin disease].

Ugeskrift for laeger - 24 Oct 2011

Meyer Martin Willy, Thyssen Jacob Pontoppidan

Abstract excerpt

Filaggrin proteins are important for the epidermal differentiation and skin barrier function. About 10% of Europeans carry loss-of-function mutations within the filaggrin gene complex. Mutations are strongly associated with ichthyosis vulgaris and atopic dermatitis as well as dry and fissured skin. No overall association with psoriasis vulgaris has been identified. The filaggrin gene discovery has been a major...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatitis, Atopic
Share to Filaggrin Proteins
Share to Intermediate Filament Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Psoriasis

Share to Risk Factors

Share to Skin Diseases

Source

Identifiers

PMID: 22027225

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Filaggrin gene mutations are frequent and increase the risk of skin disease].PMID 22027225Read ↗

Filaggrin mutations and the skin.Semantic proximity Read ↗

Atopic eczema and the filaggrin story.Semantic proximity Read ↗

Filaggrin loss-of-function mutations and association with allergic diseases.Semantic proximity Read ↗

The role of filaggrin in the skin barrier and disease development.Semantic proximity Read ↗

Filaggrin mutations associated with skin and allergic diseases.Semantic proximity Read ↗

Breaking the (un)sound barrier: filaggrin is a major gene for atopic dermatitis.Semantic proximity Read ↗

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitisSemantic proximity Read ↗

[Mutations in the gene encoding filaggrin cause ichthyosis vulgaris].Semantic proximity Read ↗

Loss-of-function mutations within the filaggrin gene and atopic dermatitis.Semantic proximity Read ↗

Common filaggrin gene loss-of-function variants are associated with skin cancer risk.Semantic proximity Read ↗

Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.Semantic proximity Read ↗

Filaggrin gene defects and the risk of developing allergic disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.