Filaggrin loss-of-function mutations and association with allergic diseases.

Abstract excerpt

Human skin constitutes a highly organized barrier against environmental agents. Its unrestricted function depends on a complex interplay between multiple proteins and lipids expressed in the terminally differentiating epithelium. Recently, attention has been drawn to the protein filaggrin, an integral part of the epidermis that plays a key role in engineering and maintaining the barrier function. Common...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Epidermal Cells
• Share to Epidermis
• Share to Filaggrin Proteins