Article
The role of filaggrin in the skin barrier and disease development.
Actas dermo-sifiliograficas - 1 Mar 2015
Armengot-Carbo M, Hernández-Martín Á, Torrelo A
Abstract excerpt
Filaggrin is a structural protein that is fundamental in the development and maintenance of the skin barrier. The function of filaggrin and its involvement in various cutaneous and extracutaneous disorders has been the subject of considerable research in recent years. Mutations in FLG, the gene that encodes filaggrin, have been shown to cause ichthyosis vulgaris, increase the risk of atopic dermatitis and other...
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