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Article

Identification of Orch3, a locus controlling dominant resistance to autoimmune orchitis, as kinesin family member 1C.

PLoS genetics - 1 Jan 2012

del Rio Roxana, McAllister Ryan D, Meeker Nathan D, Wall Emma H, Bond Jeffrey P, Kyttaris Vasileios C, Tsokos George C, Tung Kenneth S K, Teuscher Cory

Abstract excerpt

Experimental autoimmune orchitis (EAO), the principal model of non-infectious testicular inflammatory disease, can be induced in susceptible mouse strains by immunization with autologous testicular homogenate and appropriate adjuvants. As previously established, the genome of DBA/2J mice encodes genes that are capable of conferring dominant resistance to EAO, while the genome of BALB/cByJ mice does not and they...

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Identifiers

PMID: 23300462
DOI: 10.1371/journal.pgen.1003140
PMCID: PMC3531464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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