Article
Multi-allelic phenotyping--a systematic approach for the simultaneous analysis of multiple induced mutations.
Methods (San Diego, Calif.) - 15 Aug 2013
Dooley Christopher M, Scahill Catherine, Fényes Fruzsina, Kettleborough Ross N W, Stemple Derek L, Busch-Nentwich Elisabeth M
Abstract excerpt
The zebrafish mutation project (ZMP) aims to generate a loss of function allele for every protein-coding gene, but importantly to also characterise the phenotypes of these alleles during the first five days of development. Such a large-scale screen requires a systematic approach both to identifying phenotypes, and also to linking those phenotypes to specific mutations. This phenotyping pipeline simultaneously...
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