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Article

The effect of folate-related SNPs on clinicopathological features, response to neoadjuvant treatment and survival in pre- and postmenopausal breast cancer patients.

Gene - 15 Apr 2013

Babyshkina Nataliya, Malinovskaya Elena, Nazarenko Mariya, Koval Mariya, Gervas Polina, Potapova Olga, Slonimskaya Elena, Cherdyntseva Nadejda

Abstract excerpt

This study aimed to investigate the relationship of ten single nucleotide polymorphisms (SNPs) in the MTHFR, MTR, MTRR, DHFR, MTHFD1, TS, RFC1 and DNMT3b genes with cancer survival, therapeutic response to neoadjuvant chemotherapy and clinicopathological characteristics in 300 pre- and postmenopausal breast cancer patients of a Russian Western Siberian population. We found that the MTHFR 677CT genotype as well as...

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Source

Identifiers

PMID: 23296054
DOI: 10.1016/j.gene.2012.12.095

Genes

MTHFD1
MTHFR
RFC1
DHFR
MTR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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