Article
The properties of human CD40-activated B cells as antigen-presenting cells are not affected by PGE2.
Oncology reports - 1 Mar 2013
Shimabukuro-Vornhagen Alexander, Draube Andreas, Liebig Tanja, Popov Alexey, Rothe Achim, von Bergwelt-Baildon Michael
Abstract excerpt
Tumor vaccination represents a promising immuno-therapeutic strategy in cancer. However, the inherent ability of many tumors to evade immune responses by suppression of immune cell function represents a major barrier. Prostaglandin E2 (PGE2) has been shown to be a critical tumor-derived immunosuppressive factor. It affects a broad range of immune cells including T...
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