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Article

Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells.

Blood - 15 Aug 2002

Scandella Elke, Men Ying, Gillessen Silke, Förster Reinhold, Groettrup Marcus

Abstract excerpt

Dendritic cells (DCs) are potent antigen-presenting cells that are able to initiate and modulate immune responses and are hence exploited as cellular vaccines for immunotherapy. Their capacity to migrate from peripheral tissues to the T-cell areas of draining lymph nodes is crucial for the priming of T lymphocytes. In this study, we investigated how the maturation of human monocyte-derived DCs (MoDCs) by several...

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Source

Identifiers

PMID: 12149218
DOI: 10.1182/blood-2001-11-0017

Genes

CCR7
CCL19
CCL21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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