Article
Reduced T-cell and dendritic cell function is related to cyclooxygenase-2 overexpression and prostaglandin E2 secretion in patients with breast cancer.
Annals of surgical oncology - 1 Mar 2004
Pockaj Barbara A, Basu Gargi D, Pathangey Latha B, Gray Richard J, Hernandez Jose L, Gendler Sandra J, Mukherjee Pinku
Abstract excerpt
BACKGROUND: In several neoplastic diseases, including breast cancer, immunosuppression correlates with disease stage, progression, and outcome. Thus, thorough analysis of immune parameters in breast cancer patients may be beneficial in designing effective anticancer immune-based therapies. METHODS: We investigated dendritic cell and T-cell function in breast cancer patients at various stages of the disease and in...
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