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Article

Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets.

Blood - 15 Aug 2002

Luft Thomas, Jefford Michael, Luetjens Petra, Toy Tracey, Hochrein Hubertus, Masterman Kelly-Anne, Maliszewski Charlie, Shortman Ken, Cebon Jonathan, Maraskovsky Eugene

Abstract excerpt

Migration of antigen (Ag)-loaded dendritic cells (DCs) from sites of infection into draining lymphoid tissues is fundamental to the priming of T-cell immune responses. We evaluated monocyte-derived DCs (MoDCs) and peripheral blood DCs (PBDCs) to respond to proinflammatory mediators, CD40L, and intact bacteria. All classes of stimuli induced DC phenotypic maturation. However, for MoDCs, only prostaglandin E(2)...

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Identifiers

PMID: 12149219
DOI: 10.1182/blood-2001-12-0360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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