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Article

Enhanced migration of human dendritic cells expressing inducible CD40.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Lapteva Natalia

Abstract excerpt

Dendritic cells (DC) are the most potent antigen-presenting cells for priming and activating naïve CD4(+) and CD8(+) T lymphocytes. This property has led to their use as a cellular vaccine in a number of clinical trials with promising results. However, the clinical efficacy of DC vaccines in patients has been unsatisfactory, probably because of a number of key deficiencies, including limited migration of ex vivo...

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Identifiers

PMID: 20686961
DOI: 10.1007/978-1-60761-786-0_5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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