Article
Dendritic cells produce eicosanoids, which modulate generation and functions of antigen-presenting cells.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Jan 2000
Harizi H, Gualde N
Abstract excerpt
Eicosanoids have been shown to be potent immunoregulatory arachidonic acid (AA) metabolites. AA is the precursor of prostaglandin E(2) (PGE(2)) and leukotriene B(4) (LTB(4)) which are able to modulate both inflammation and the immune response. Dendritic cells process and present antigens to T lymphocytes. They are highly specialized antigen-presenting cells (APC) and usually considered as 'professional APC'. In...
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