Article
Allelotype of human ovarian cancer.
Cancer research - 1 Oct 1991
Sato T, Saito H, Morita R, Koi S, Lee J H, Nakamura Y
Abstract excerpt
In order to determine which chromosome(s) carries a tumor suppressor gene(s) for human ovarian cancer, we examined loss of heterozygosity in 37 tumors with a set of polymorphic DNA markers which cover each autosomal chromosome arm partially. Frequent losses were observed in chromosomes 4p (42%),...
Topics
- Adenocarcinoma
- Adenocarcinoma, Mucinous
- Chromosome Deletion
- Chromosome Mapping
- Cystadenocarcinoma
- DNA Probes
- Female
- Genes, Suppressor
- Genetic Markers
- Genotype
- Heterozygote
- Humans
- Ovarian Neoplasms