Article
Allelotype of human ovarian cancer.
Cancer research - 1 Oct 1991
Sato T, Saito H, Morita R, Koi S, Lee J H, Nakamura Y
Abstract excerpt
In order to determine which chromosome(s) carries a tumor suppressor gene(s) for human ovarian cancer, we examined loss of heterozygosity in 37 tumors with a set of polymorphic DNA markers which cover each autosomal chromosome arm partially. Frequent losses were observed in chromosomes 4p (42%), 6p (50%), 7p (43%), 8q (31%), 12p (38%), 12q (33%), 16p (33%), 16q (38%), 17p (46%), 17q (39%), and 19p (34%). In...
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