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Article

iLOCi: a SNP interaction prioritization technique for detecting epistasis in genome-wide association studies.

BMC genomics - 1 Jan 2012

Piriyapongsa Jittima, Ngamphiw Chumpol, Intarapanich Apichart, Kulawonganunchai Supasak, Assawamakin Anunchai, Bootchai Chaiwat, Shaw Philip J, Tongsima Sissades

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) do not provide a full account of the heritability of genetic diseases since gene-gene interactions, also known as epistasis are not considered in single locus GWAS. To address this problem, a considerable number of methods have been developed for identifying disease-associated gene-gene interactions. However, these methods typically fail to identify interacting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23281813
DOI: 10.1186/1471-2164-13-S7-S2
PMCID: PMC3521387

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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