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Article

Prioritizing tests of epistasis through hierarchical representation of genomic redundancies.

Nucleic acids research - 21 Aug 2017

Cowman Tyler, Koyutürk Mehmet

Abstract excerpt

Epistasis is defined as a statistical interaction between two or more genomic loci in terms of their association with a phenotype of interest. Epistatic loci that are identified using data from Genome-Wide Association Studies (GWAS) provide insights into the interplay among multiple genetic factors, with applications including assessment of susceptibility to complex diseases, decision making in precision...

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Identifiers

PMID: 28605458
DOI: 10.1093/nar/gkx505
PMCID: PMC5737499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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